मेटोप्रोलोल सक्सिनेट एपीआई

Metoprolol Succinate USP is the United States Pharmacopeia USPgrade version of Metoprolol Succinate a beta1 selective adrenergic receptor blocker betablocker It is commonly prescribed to manage several cardiovascular conditions Key Details Generic Name Metoprolol Succinate Brand Names ToprolXL others USP Indicates it meets the quality purity strength and consistency standards set by the United States Pharmacopeia Indications Metoprolol Succinate is used to treat Hypertension high blood pressure Angina pectoris chest pain Heart failure particularly NYHA Class II or III Postmyocardial infarction heart attack management to reduce risk of death Pharmacology Class Beta1 selective betablocker Mechanism Reduces heart rate cardiac output and blood pressure by blocking beta1 adrenergic receptors in the heart Formulation Extendedrelease ER tablets for oncedaily dosing Common Dosages HypertensionAngina Typically 25100 mg once daily Heart Failure Starting at 12525 mg once daily titrated up as tolerated to a target dose eg 200 mgday Important Notes Should not be abruptly discontinued as it can cause rebound hypertension or exacerbate angina Adjust dose with caution in patients with bradycardia hypotension or renalhepatic impairment May cause side effects like fatigue dizziness bradycardia depression or cold extremities Would you like detailed pharmacokinetics brand comparisons or patient counseling information